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3clpro  (BPS Bioscience)


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    Structured Review

    BPS Bioscience 3clpro
    3clpro, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 95/100, based on 57 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/3clpro/3CL+Protease%2C+Untagged+(SARS-CoV-2)+Assay+Kit/pmc12854628-147-1-5
    Average 95 stars, based on 57 article reviews
    3clpro - by Bioz Stars, 2026-09
    95/100 stars

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    Related Articles

    Inhibition:

    Article Title: Method and combination for the suppression of COVID-19 virus
    Article Snippet: .. A 3CLpro (Cat. #78042-1) assay kit (BPS Bioscience, CA, USA) was used for the single use experiment of the norvancomycin, and it showed 20% to 30% inhibition at 3 μM to 90 μM (see the yellow bars in the middle of FIG. 4). ..

    Enzymatic Assay:

    Article Title: Identification of SARS-CoV-2 M pro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2.
    Article Snippet: .. SARS-CoV-2 Mpro/3CLpro and human cysteine protease enzyme assay The 3CLpro (SARS-CoV-2) assay kit (BPS Bioscience, San Diego CA, cat. no. 78042-2) is designed to measure 3CLpro activity and identify inhibitors of this enzyme, while human cathepsin L inhibitor screening kit (abcam, cat. Cambridge, UK, No. ab197012) and human calpain Nature Communications | (2023) 14:1076 8 activity assay kit (AnaSpec. ..

    Activity Assay:

    Article Title: Identification of SARS-CoV-2 M pro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2.
    Article Snippet: .. SARS-CoV-2 Mpro/3CLpro and human cysteine protease enzyme assay The 3CLpro (SARS-CoV-2) assay kit (BPS Bioscience, San Diego CA, cat. no. 78042-2) is designed to measure 3CLpro activity and identify inhibitors of this enzyme, while human cathepsin L inhibitor screening kit (abcam, cat. Cambridge, UK, No. ab197012) and human calpain Nature Communications | (2023) 14:1076 8 activity assay kit (AnaSpec. ..

    Article Title: Dual-Reporter System for Real-Time Monitoring of SARS-CoV-2 Main Protease Activity in Live Cells Enables Identification of an Allosteric Inhibition Path.
    Article Snippet: The SARS-CoV-2 pandemic is an ongoing threat to global health, and the continuing emergence of contagious variants highlights the urgent need for additional antiviral therapy to attenuate COVID-19 disease.. The SARS-CoV-2 main protease (3CLpro) presents an attractive target for such therapy due to its high sequence conservation and key role in the viral life cycle.. In this study, we designed a fluorescent−luminescent cell-based reporter for the detection and quantification of 3CLpro intracellular activity.

    Article Title: Impact of Single Halogen Atom Substitutions on Antiviral Profile of Inhibitors Targeting SARS-CoV‑2 Main Protease
    Article Snippet: .. The 3CLpro (SARS-CoV-2) assay kits (BPS Bioscience, San Diego CA, cat. no. 78042-1 for M pro WT and no. 78350-1 for M pro B.1.1.529 ) are designed to measure 3CLpro activity and identify inhibitors of this enzyme. ..

    Article Title: Identification of SARS-CoV-2 M pro inhibitors containing P1’ 4-fluorobenzothiazole moiety highly active against SARS-CoV-2
    Article Snippet: .. The 3CLpro (SARS-CoV-2) assay kit (BPS Bioscience, San Diego CA, cat. no. 78042-2) is designed to measure 3CLpro activity and identify inhibitors of this enzyme, while human cathepsin L inhibitor screening kit (abcam, cat. Cambridge, UK, No. ab197012) and human calpain activity assay kit (AnaSpec. ..

    In Vitro:

    Article Title: Dual-Reporter System for Real-Time Monitoring of SARS-CoV-2 Main Protease Activity in Live Cells Enables Identification of an Allosteric Inhibition Path.
    Article Snippet: The SARS-CoV-2 pandemic is an ongoing threat to global health, and the continuing emergence of contagious variants highlights the urgent need for additional antiviral therapy to attenuate COVID-19 disease.. The SARS-CoV-2 main protease (3CLpro) presents an attractive target for such therapy due to its high sequence conservation and key role in the viral life cycle.. In this study, we designed a fluorescent−luminescent cell-based reporter for the detection and quantification of 3CLpro intracellular activity.

    Incubation:

    Article Title: Dual-Reporter System for Real-Time Monitoring of SARS-CoV-2 Main Protease Activity in Live Cells Enables Identification of an Allosteric Inhibition Path.
    Article Snippet: The SARS-CoV-2 pandemic is an ongoing threat to global health, and the continuing emergence of contagious variants highlights the urgent need for additional antiviral therapy to attenuate COVID-19 disease.. The SARS-CoV-2 main protease (3CLpro) presents an attractive target for such therapy due to its high sequence conservation and key role in the viral life cycle.. In this study, we designed a fluorescent−luminescent cell-based reporter for the detection and quantification of 3CLpro intracellular activity.



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